Genetic defects rise with fad-driven inbreeding of dogs in Japan

Genetic defects rise with fad-driven inbreeding of dogs in Japan - IHT, December 27, 2006
Care for a Chihuahua with a blue hue? How about a teacup poodle so tiny it will fit into a purse — the canine equivalent of a bonsai? The Japanese sure do.
Rare and unique dogs are highly prized here and can set buyers back more than ¥1 million, or about $8,400. But the problem is what often arrives in the same litter: genetically defective sister and brother puppies born with missing paws or faces lacking eyes and a nose.
There have been dogs with brain disorders so severe that they spent all day running in circles, and others with bones so frail they dissolved in their bodies...
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